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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37507
Proper Citation: RRID:MMRRC_037507-MU
Description: Mus musculus with name B6.Cg-Prltm1Hmn Tg(PRL)30Greg/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Developmental Biology, Endocrine Deficiency, Immunology and Inflammation, Models for Human Disease, Obesity, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal mammary gland morphology [MP:0000627]| abnormal mammary gland development [MP:0000628]| abnormal pituitary gland morphology [MP:0000633]| pituitary gland hyperplasia [MP:0000635]| enlarged pituitary gland [MP:0000636]| small prostate gland ventral lobe [MP:0000661]| abnormal branching of the mammary ductal tree [MP:0000662]| failure of embryo implantation [MP:0001728]| abnormal pituitary secretion [MP:0001746]| female infertility [MP:0001926]| abnormal estrous cycle [MP:0001927]| increased pituitary adenoma incidence [MP:0002041]| decreased circulating luteinizing hormone level [MP:0002773]| decreased circulating estrogen level [MP:0003371]| decreased liver weight [MP:0003402]| decreased seminal vesicle weight [MP:0004910]| decreased circulating prolactin level [MP:0005121]| decreased follicle stimulating hormone level [MP:0005130]| decreased luteinizing hormone level [MP:0005132]| decreased prolactin level [MP:0005138]| decreased circulating estradiol level [MP:0005181]| decreased dopamine level [MP:0005643]| abnormal gonadotroph morphology [MP:0008325]| decreased lactotroph cell number [MP:0008332]| increased pituitary gland weight [MP:0008939]| prolonged estrous cycle [MP:0009006]| short estrous cycle [MP:0009007]| prolonged proestrus [MP:0009014]| prolonged estrus [MP:0009017]| pituitary gland hypertrophy [MP:0013336]
Affected Gene: |Prl|PRL|
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)