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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37405
Proper Citation: RRID:MMRRC_037405-JAX
Description: Mus musculus with name B6.Cg-Pex1tm1.1Sjms/Mmjax from MMRRC.
Species: Mus musculus
Notes: Research areas: Metabolism, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Phenotype: cholestasis [MP:0000610]| decreased body weight [MP:0001262]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| bile duct proliferation [MP:0003255]| abnormal rod electrophysiology [MP:0004021]| abnormal cone electrophysiology [MP:0004022]| increased fatty acid level [MP:0005281]| decreased fatty acid level [MP:0005282]| increased saturated fatty acid level [MP:0005284]| abnormal intestinal lipid absorption [MP:0005342]| abnormal bile salt homeostasis [MP:0005365]| abnormal circulating phospholipid level [MP:0006084]| retinal cone cell degeneration [MP:0008444]| abnormal retinal rod cell outer segment morphology [MP:0008456]
Affected Gene: Pex1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
Email: info_at_ dknet.org
