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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36498
Proper Citation: RRID:MMRRC_036498-MU
Description: Mus musculus with name B6.129P2-Slc39a4tm2Gka/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cell Biology, Developmental Biology, Metabolism, Models for Human Disease, Research Tools; Mutation Type: other ; Collection:
Phenotype: abnormal liver morphology [MP:0000598]| weight loss [MP:0001263]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| increased liver copper level [MP:0003066]| decreased liver copper level [MP:0003067]| abnormal copper level [MP:0003952]| decreased bone mass [MP:0004016]| decreased muscle weight [MP:0004232]| abnormal small intestine crypts of Lieberkuhn morphology [MP:0004841]| abnormal Paneth cell morphology [MP:0004843]| abnormal mineral homeostasis [MP:0005636]| abnormal small intestinal villus morphology [MP:0008108]| increased liver iron level [MP:0008807]| abnormal zinc homeostasis [MP:0009615]| abnormal small intestinal crypt cell proliferation [MP:0010157]| decreased intestine copper level [MP:0010248]| lethality at weaning [MP:0011083]| complete penetrance [MP:0020385]
Affected Gene: Slc39a4
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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