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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36421
Proper Citation: RRID:MMRRC_036421-UCD
Description: Mus musculus with name C57BL/6JSfdAnu-Muc2wnn/AnuApbMmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: chemically induced mutation ; Collection: NHMRC Australian PhenomeBank
Phenotype: decreased hematocrit [MP:0000208]| increased leukocyte cell number [MP:0000218]| abnormal intestine morphology [MP:0000477]| rectal prolapse [MP:0000493]| abnormal colon morphology [MP:0000495]| abnormal intestinal mucosa morphology [MP:0000511]| intestinal ulcer [MP:0000512]| increased circulating triglyceride level [MP:0001552]| abnormal digestive system physiology [MP:0001663]| abnormal intestinal absorption [MP:0001666]| premature death [MP:0002083]| colitis [MP:0002816]| melena [MP:0003292]| rectal hemorrhage [MP:0003293]| abnormal intestinal goblet cell morphology [MP:0003449]| abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842]| increased lymphocyte cell number [MP:0005013]| diarrhea [MP:0005036]| increased susceptibility to induced colitis [MP:0008537]| increased tumor necrosis factor secretion [MP:0008560]| increased interferon-gamma secretion [MP:0008566]| increased interleukin-1 beta secretion [MP:0008657]| increased interleukin-13 secretion [MP:0008672]| abnormal enterocyte proliferation [MP:0008883]| increased enterocyte apoptosis [MP:0008885]| abnormal endoplasmic reticulum morphology [MP:0009378]| ileum inflammation [MP:0009482]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009766]| abnormal intestine physiology [MP:0010155]| increased susceptibility to weight loss [MP:0010180]| dilated mitochondria [MP:0011632]| abnormal mitochondrial crista morphology [MP:0011635]| decreased colon length [MP:0013956]| increased endoplasmic reticulum stress [MP:0020354]
Affected Gene: Muc2
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)