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URL: https://www.mmrrc.org/catalog/cellLineSDS.php?mmrrc_id=36284
Proper Citation: RRID:MMRRC_036284-JAX
Description: Mus musculus with name B6;129-Mycntm1Psk Myctm2Fwa cDKO2 mES cells from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology; Mutation Type: other ; Collection:
Phenotype: abnormal malleus morphology [MP:0000029]| abnormal frontal bone morphology [MP:0000107]| abnormal parietal bone morphology [MP:0000109]| belly spot [MP:0000373]| short snout [MP:0000445]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| no abnormal phenotype detected [MP:0002169]| variable body spotting [MP:0002940]| abnormal coronal suture morphology [MP:0003840]| small nasal bone [MP:0004470]| short nasal bone [MP:0004471]| abnormal auditory brainstem response [MP:0004738]| decreased B cell proliferation [MP:0005093]| abnormal middle ear ossicle morphology [MP:0005105]| small cranium [MP:0005352]| conductive hearing impairment [MP:0006326]| absent pinna reflex [MP:0006358]| small malleus [MP:0008372]| short malleus manubrium [MP:0008375]| small malleus manubrium [MP:0008376]| decreased spleen germinal center size [MP:0008484]| microcephaly [MP:0000433]| decreased brain size [MP:0000774]| abnormal cerebral cortex morphology [MP:0000788]| abnormal cerebellum morphology [MP:0000849]| small cerebellum [MP:0000852]| abnormal cerebellum development [MP:0000854]| abnormal cerebellar foliation [MP:0000857]| abnormal cerebellum external granule cell layer morphology [MP:0000872]| abnormal cerebellar Purkinje cell layer [MP:0000875]| decreased Purkinje cell number [MP:0000880]| ectopic Purkinje cell [MP:0000885]| abnormal cerebellar granule layer morphology [MP:0000886]| abnormal cerebellar molecular layer [MP:0000889]| abnormal lung morphology [MP:0001175]| abnormal lung development [MP:0001176]| microphthalmia [MP:0001297]| postnatal growth retardation [MP:0001732]| abnormal pulmonary alveolus epithelial cell morphology [MP:0002273]| premature neuronal precursor differentiation [MP:0003424]| abnormal embryonic neuroepithelium morphology [MP:0004261]| abnormal neuronal precursor proliferation [MP:0004948]| decreased neuronal precursor cell number [MP:0004981]| abnormal lung epithelium morphology [MP:0006382]| abnormal cortical ventricular zone morphology [MP:0008458]| decreased survivor rate [MP:0008770]| abnormal neuron differentiation [MP:0009937]| decreased type II pneumocyte number [MP:0010811]| decreased type I pneumocyte number [MP:0010816]| abnormal branching involved in lung morphogenesis [MP:0011024]| neonatal lethality [MP:0011087]| complete penetrance [MP:0011088]| neonatal lethality [MP:0012703]
Affected Gene: |Mycn||Myc
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)