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Organism Name
B6;129S4-Ptpn11tm1Bgn/Mmjax
RRID:MMRRC_032104-JAX RRID Copied  
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RRID:MMRRC_032104-JAX
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=32104

Proper Citation: RRID:MMRRC_032104-JAX

Description: Mus musculus with name B6;129S4-Ptpn11tm1Bgn/Mmjax from MMRRC.

Species: Mus musculus

Notes: Research areas: Cardiovascular, Developmental Biology, Hematology, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:

Phenotype: increased leukocyte cell number [MP:0000218]| increased neutrophil cell number [MP:0000219]| abnormal heart morphology [MP:0000266]| abnormal heart development [MP:0000267]| double outlet right ventricle [MP:0000284]| increased cell proliferation [MP:0000351]| flattened snout [MP:0000447]| small liver [MP:0000601]| enlarged spleen [MP:0000691]| decreased body length [MP:0001258]| decreased body weight [MP:0001262]| hepatic necrosis [MP:0001654]| hemorrhage [MP:0001914]| hydrops fetalis [MP:0002192]| thin myocardium [MP:0002652]| decreased cardiomyocyte apoptosis [MP:0003223]| thin myocardium compact layer [MP:0004057]| increased lymphocyte cell number [MP:0005013]| pericardial effusion [MP:0005312]| small cranium [MP:0005352]| abnormal common myeloid progenitor cell morphology [MP:0006410]| abnormal cardiac epithelial to mesenchymal transition [MP:0008825]| myeloid hyperplasia [MP:0010373]| ventricular septal defect [MP:0010402]| atrial septal defect [MP:0010403]| atrioventricular septal defect [MP:0010412]| enlarged mitral valve [MP:0010618]| perinatal lethality [MP:0011090]| incomplete penetrance [MP:0011098]| embryonic lethality during organogenesis [MP:0030166]| complete penetrance [MP:0030189]

Affected Gene: Ptpn11

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)