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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=9983
Proper Citation: RRID:MMRRC_009983-MU
Description: Mus musculus with name B6.129S4-Bcl2l2Gt(ROSA)41Sor/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cell Biology, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Gene Trap ; Collection:
Phenotype: abnormal cerebellum morphology [MP:0000849]| abnormal cerebellar Purkinje cell layer [MP:0000875]| abnormal Purkinje cell morphology [MP:0000877]| small testis [MP:0001147]| Leydig cell hyperplasia [MP:0001152]| small seminiferous tubules [MP:0001153]| decreased body size [MP:0001265]| ataxia [MP:0001393]| abnormal gait [MP:0001406]| increased circulating follicle stimulating hormone level [MP:0001750]| male infertility [MP:0001925]| decreased germ cell number [MP:0002209]| abnormal seminiferous tubule morphology [MP:0002216]| absent Leydig cells [MP:0002785]| abnormal motor learning [MP:0002804]| decreased testis weight [MP:0004852]| decreased male germ cell number [MP:0004901]| decreased seminal vesicle weight [MP:0004910]| abnormal CNS synapse formation [MP:0004996]| decreased CNS synapse formation [MP:0004998]| bradykinesia [MP:0005156]| Sertoli cell hypoplasia [MP:0005250]| abnormal mitochondrion morphology [MP:0006035]| abnormal Purkinje cell dendrite morphology [MP:0008572]| abnormal Sertoli cell barrier morphology [MP:0020355]
Affected Gene: Bcl2l2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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