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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=194
Proper Citation: RRID:MMRRC_000194-UCD
Description: Mus musculus with name STOCK Itgb8tm1Lfr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cell Biology, Developmental Biology, Hematology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: cleft palate [MP:0000111]| abnormal angiogenesis [MP:0000260]| failure of vascular branching [MP:0000264]| abnormal heart morphology [MP:0000266]| absent floor plate [MP:0000926]| abnormal cardiovascular system physiology [MP:0001544]| abnormal blood vessel morphology [MP:0001614]| decreased embryo size [MP:0001698]| abnormal placenta morphology [MP:0001711]| abnormal visceral yolk sac morphology [MP:0001718]| pale yolk sac [MP:0001722]| hydroencephaly [MP:0001891]| intracranial hemorrhage [MP:0001915]| intracerebral hemorrhage [MP:0001916]| abnormal extraembryonic tissue morphology [MP:0002086]| no abnormal phenotype detected [MP:0002169]| abnormal astrocyte morphology [MP:0002182]| abnormal chorioallantoic fusion [MP:0002824]| impaired basement membrane formation [MP:0003044]| abnormal vitelline vasculature morphology [MP:0003229]| abnormal placenta vasculature [MP:0003231]| abnormal radial glial cell morphology [MP:0003648]| abnormal capillary morphology [MP:0003658]| abnormal embryonic/fetal subventricular zone morphology [MP:0004274]| abnormal brain vasculature morphology [MP:0004950]| hemopericardium [MP:0005244]| abnormal heart ventricle morphology [MP:0005294]| abnormal vascular endothelial cell morphology [MP:0006055]| increased vascular endothelial cell number [MP:0006056]| abnormal placental labyrinth vasculature morphology [MP:0008803]| palatal shelves fail to meet at midline [MP:0009888]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011108]| embryonic lethality during organogenesis [MP:0011380]| incomplete penetrance [MP:0011523]| enlarged brain ventricles [MP:0012501]
Affected Gene: Itgb8
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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