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Proper Citation: RRID:MGI:6287973
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal kidney morphology, abnormal macrophage physiology, increased circulating interleukin-12b level, abnormal circulating chemokine level, decreased body weight, decreased circulating interleukin-10 level, glomerulonephritis, increased IgG level, increased anti-double stranded DNA antibody level, abnormal renal glomerulus morphology, increased susceptibility to systemic lupus erythematosus, increased anti-nuclear antigen antibody level, increased autoantibody level, increased urine protein level, increased neutrophil cell number, increased blood urea nitrogen level, increased circulating creatinine level, increased monocyte cell number, increased lymphocyte cell number, increased circulating interleukin-1 beta level, increased circulating interleukin-6 level
Affected Gene: Atg7, Lyz2
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No rating or validation information has been found for Atg7tm1Tchi/Atg7tm1Tchi; Lyz2tm1(cre)Ifo/Lyz2+.
No alerts have been found for Atg7tm1Tchi/Atg7tm1Tchi; Lyz2tm1(cre)Ifo/Lyz2+.
Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI