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Proper Citation: RRID:MGI:6159568
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: hyperkeratosis, decreased birth weight, impaired skin barrier function, weight loss, abnormal stratum corneum lipid matrix formation, abnormal skin appearance, thick epidermis stratum spinosum, abnormal keratohyalin granule morphology, abnormal magnesium ion homeostasis, decreased keratohyalin granule size, increased keratohyalin granule number, abnormal epidermal lamellar body morphology, abnormal epidermis stratum granulosum morphology, abnormal corneocyte morphology, neonatal lethality, complete penetrance, decreased ceramide level, shiny skin, abnormal keratinocyte differentiation, decreased sphingosine level, increased ceramide level, increased sphingosine level
Affected Gene: Nipal4
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No rating or validation information has been found for Nipal4tm1Akih/Nipal4tm1Akih.
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI