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Proper Citation: RRID:MGI:5805456
Description: Allele Detail: Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Transgenic This is a legacy resource.
Phenotype: increased anti-nuclear antigen antibody level, decreased salivation, increased interleukin-17 secretion, demyelination, lacrimal gland inflammation, increased susceptibility to autoimmune disorder, increased autoantibody level, salivary gland inflammation, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased IgG level, decreased CD8-positive, alpha-beta T cell number, behavior/neurological phenotype, abnormal salivary gland physiology, abnormal CD4-positive, alpha beta T cell morphology, increased interferon-gamma secretion, increased effector memory CD4-positive, alpha-beta T cell number, decreased interferon-gamma secretion, lung inflammation, altered susceptibility to viral infection, abnormal T-helper 17 cell physiology, decreased IgG2c level, decreased interleukin-10 secretion, decreased IgG3 level
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No rating or validation information has been found for Tg(CD2-Rorc)#Staka.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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