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Proper Citation: RRID:MGI:5605688
Description: Allele Detail: Targeted, Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted, Transgenic This is a legacy resource.
Phenotype: decreased fatty acid oxidation, abnormal bile canaliculus morphology, increased circulating aspartate transaminase level, abnormal endoplasmic reticulum morphology, decreased liver cholesterol level, decreased liver glycogen level, decreased liver triglyceride level, decreased susceptibility to diet-induced obesity, abnormal kidney development, hypoglycemia, increased circulating alanine transaminase level, decreased circulating insulin-like growth factor I level, abnormal hepatocyte morphology, increased circulating alkaline phosphatase level, decreased circulating triglyceride level, small liver, abnormal hepatobiliary system development, abnormal glucose tolerance, abnormal liver sinusoid morphology, abnormal thymus development, decreased circulating HDL cholesterol level, decreased body size, postnatal lethality, incomplete penetrance, perinatal lethality, incomplete penetrance, decreased circulating serum albumin level, abnormal liver morphology, decreased circulating cholesterol level, pale liver, increased insulin sensitivity, increased hepatocyte apoptosis, increased circulating growth hormone level, increased circulating bilirubin level, decreased brown adipose tissue amount
Affected Gene: Speer6-ps1, Srsf3
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No rating or validation information has been found for Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+; Srsf3tm1Pjln/Srsf3tm1Pjln.
No alerts have been found for Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+; Srsf3tm1Pjln/Srsf3tm1Pjln.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI