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Proper Citation: RRID:MGI:5296231
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased B cell number, increased IgE level, abnormal effector T cell morphology, abnormal Peyer's patch morphology, increased IgG2a level, enlarged spleen, bile duct hyperplasia, abnormal intestine morphology, increased interleukin-12b secretion, enlarged lymph nodes, increased monocyte cell number, increased granulocyte number, increased IgG level, abnormal complement pathway, increased IgA level, increased B cell proliferation, increased fibroblast apoptosis, increased anti-nuclear antigen antibody level, increased spleen white pulp amount, immune system phenotype, premature death, increased T follicular helper cell number, increased anti-double stranded DNA antibody level, increased germinal center B cell number, increased interleukin-6 secretion, increased IgM level, increased IgG1 level, increased plasma cell number, increased tumor necrosis factor secretion, liver fibrosis, vasculitis, abnormal blood vessel morphology, increased immunoglobulin level, abnormal immune system morphology, glomerulonephritis, abnormal plasma cell morphology, abnormal spleen germinal center morphology, increased spleen weight, increased IgG3 level, increased IgG2b level, increased spleen red pulp amount
Affected Gene: Tnip1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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