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Proper Citation: RRID:MGI:4950418
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: premature death, slow postnatal weight gain, decreased erythrocyte cell number, decreased double-positive T cell number, increased sensitivity to induced cell death, pallor, increased cellular sensitivity to alkylating agents, increased small intestinal crypt cell apoptosis, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, alpha-beta T cell number, decreased T cell number, decreased leukocyte cell number, thrombocytopenia, pancytopenia, abnormal DNA repair, decreased double-negative T cell number, postnatal lethality, incomplete penetrance, increased cellular sensitivity to ionizing radiation, decreased granulocyte number, arrested B cell differentiation, small lymphoid organs, increased cellular sensitivity to ultraviolet irradiation, increased mortality induced by ionizing radiation, decreased macrophage cell number, decreased gamma-delta T cell number, decreased hematopoietic stem cell number, decreased bone marrow cell number, abnormal immunoglobulin V(D)J recombination, hyperpigmentation, abnormal hematopoietic stem cell physiology, decreased lymphocyte cell number, decreased mature B cell number
Affected Gene: Prkdc
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No rating or validation information has been found for Prkdctm1.1Bpcc/Prkdctm1.1Bpcc.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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