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Proper Citation: RRID:MGI:4366263
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: kidney failure, increased blood urea nitrogen level, altered response of heart to induced stress, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to induced colitis, weight loss, increased leukocyte cell number, decreased hematocrit, decreased prostaglandin level, enlarged spleen, abnormal colon morphology, anemia, peritoneal inflammation, decreased lactate dehydrogenase level, decreased susceptibility to injury, decreased susceptibility to induced pancreatitis, increased tumor necrosis factor secretion, decreased incidence of tumors by chemical induction, abnormal enzyme/coenzyme level, pancreas necrosis, increased sensitivity to xenobiotic induced morbidity/mortality, abnormal kidney cortex morphology, abnormal proximal convoluted tubule morphology, abnormal renal glomerulus morphology, behavior/neurological phenotype, cardiovascular system phenotype, decreased kidney weight, decreased renal glomerular filtration rate, dilated renal tubules, glomerulosclerosis, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased circulating creatinine level, increased heart weight, kidney cortex cysts, kidney cysts, premature death, proximal convoluted tubule brush border loss, renal glomerulus cysts, renal glomerulus fibrosis, renal glomerulus hypertrophy, renal interstitial fibrosis, renal tubule atrophy, renal tubule hypertrophy, renal/urinary system phenotype, abnormal kidney development, kidney degeneration, decreased susceptibility to endotoxin shock, decreased prostaglandin level, muscle phenotype, increased incidence of induced tumors, abnormal keratinocyte differentiation, increased susceptibility to induced colitis
Affected Gene: Ptgs2
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No rating or validation information has been found for Ptgs2tm1Unc/Ptgs2tm1Unc.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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