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Proper Citation: RRID:MGI:3768242
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal bone marrow cell morphology/development, lung inflammation, liver inflammation, lethargy, increased susceptibility to bacterial infection, increased immunoglobulin level, myeloid hyperplasia, decreased interleukin-2 secretion, abnormal humoral immune response, abnormal cytokine secretion, postnatal growth retardation, preweaning lethality, incomplete penetrance, premature death, rough coat, abnormal lymph organ size, abnormal lymphocyte physiology, abnormal inflammatory response, decreased interleukin-4 secretion, increased IgE level, increased B cell proliferation, extramedullary hematopoiesis, enlarged spleen, enlarged lymph nodes, decreased single-positive T cell number, increased IgG1 level, decreased tumor necrosis factor secretion, decreased IgG3 level, decreased T cell proliferation, decreased erythrocyte cell number
Affected Gene: Nfkb1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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