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Proper Citation: RRID:MGI:3759844
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal sleep pattern, large intestinal inflammation, increased colon adenocarcinoma incidence, cecum inflammation, abnormal chemokine level, decreased susceptibility to induced choroidal neovascularization, increased circulating interferon-gamma level, abnormal cytokine level, decreased mean systemic arterial blood pressure, increased circulating interleukin-2 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, abnormal regulatory T cell physiology, increased susceptibility to parasitic infection, increased susceptibility to induced colitis, impaired adaptive thermogenesis, decreased vasoconstriction, increased circulating interleukin-6 level, impaired coordination, increased circulating interleukin-1 alpha level, increased circulating interleukin-1 beta level, impaired exercise endurance, increased circulating interleukin-12 level, abnormal cytokine level, increased circulating interleukin-1 beta level, slow postnatal weight gain, abnormal neuron physiology, increased cerebral infarction size, increased circulating interleukin-17 level, increased susceptibility to neuronal excitotoxicity, rectal prolapse, increased vasoconstriction
Affected Gene: Il10
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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