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Proper Citation: RRID:MGI:3711773
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: anterior subcapsular cataracts, absent Schlemm's canal, absent optic nerve, absent trabecular meshwork, cataract, anterior iris synechia, corneal opacity, decreased cornea thickness, hypoplastic trabecular meshwork, iris hypoplasia, irregularly shaped pupil, ocular hypertension, opacity of vitreous body, persistence of hyaloid vascular system, retinal detachment, thin retinal ganglion layer, anterior cortical cataracts, abnormal anterior eye segment morphology, abnormal canal of Schlemm morphology, abnormal cornea morphology, abnormal eye electrophysiology, abnormal eye morphology, abnormal iridocorneal angle, abnormal line of Schwalbe morphology, abnormal optic nerve morphology, abnormal optic disk morphology, abnormal placement of pupils, abnormal posterior eye segment morphology, abnormal retinal photoreceptor layer morphology, abnormal retinal blood vessel pattern, abnormal vitreous body morphology, thin retinal inner nuclear layer, abnormal retina morphology, impaired hearing, reduced female fertility, decreased vestibular hair cell stereocilia number, abnormal sensory neuron innervation pattern, abnormal organ of Corti morphology, abnormal fertility/fecundity, decreased litter size, abnormal vestibulocollic reflex, circling, increased or absent threshold for auditory brainstem response, short frontal bone, microphthalmia, anophthalmia, abnormal eye size, abnormal seminiferous tubule morphology, abnormal male reproductive system morphology, abnormal prostate gland anterior lobe morphology, kidney atrophy, hydronephrosis, kidney cysts, single kidney, perinatal lethality, incomplete penetrance, polydactyly, short nasal bone
Affected Gene: Bmp4
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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