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Proper Citation: RRID:MGI:3701944
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: hepatic steatosis, abnormal crypts of Lieberkuhn morphology, increased susceptibility to weight gain, large intestinal inflammation, abnormal mitochondrion morphology, abnormal mitophagy, abnormal respiratory electron transport chain, neoplasm, increased sensitivity to xenobiotic induced morbidity/mortality, abnormal mitochondrial physiology, increased susceptibility to induced colitis, hyperglycemia, increased liver weight, increased circulating insulin level, increased body weight, abnormal oxidative phosphorylation, increased body fat mass, abnormal renal fat pad morphology, impaired glucose tolerance, oxidative stress, abnormal cell morphology, increased susceptibility to diet-induced non-insulin dependent diabetes, increased mitochondria number, insulin resistance, increased susceptibility to diet-induced obesity, abnormal intestinal mucosa morphology, increased colon adenoma incidence, oxidative stress, increased incidence of tumors by chemical induction, abnormal epididymal fat pad morphology
Affected Gene: Trp53inp1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI