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Proper Citation: RRID:MGI:3696100
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased interleukin-10 secretion, increased sensitivity to xenobiotic induced morbidity/mortality, enlarged mesenteric lymph nodes, abnormal type IV hypersensitivity reaction, increased susceptibility to type IV hypersensitivity reaction, glomerulonephritis, albuminuria, abnormal urine homeostasis, increased susceptibility to parasitic infection, abnormal immunoglobulin level, abnormal immune tolerance, abnormal dendritic cell antigen presentation, enlarged spleen, increased interleukin-4 secretion, increased leukocyte cell number, increased monocyte cell number, decreased interleukin-10 secretion, decreased interferon-gamma secretion, abnormal cytokine secretion, abnormal humoral immune response, abnormal Langerhans cell physiology, increased interleukin-12 secretion, abnormal response to injury, abnormal dendritic cell chemotaxis, immune system phenotype, increased susceptibility to bacterial infection, abnormal spleen morphology, abnormal spleen white pulp morphology, abnormal spleen red pulp morphology, decreased vertical activity, extramedullary hematopoiesis, abnormal response to new environment, abnormal dendritic cell physiology, increased granulocyte number, increased susceptibility to parasitic infection induced morbidity/mortality, abnormal macrophage chemotaxis, increased NK T cell number, skeletal muscle fibrosis, abnormal nitric oxide homeostasis, abnormal redox activity, decreased susceptibility to injury, increased fear-related response, increased susceptibility to bacterial infection induced morbidity/mortality, pale spleen, impaired skeletal muscle regeneration, decreased length of allograft survival, stomach inflammation, increased circulating interleukin-6 level, abnormal circulating cytokine level
Affected Gene: Ifng
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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