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Proper Citation: RRID:MGI:3663760
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased urine sodium level, increased heart rate, increased dopamine level, increased circulating noradrenaline level, increased circulating adrenaline level, increased circulating antidiuretic hormone level, increased circulating noradrenaline level, abnormal cardiovascular system morphology, increased circulating renin level, increased dopamine level, renal fibrosis, increased heart rate, heart left ventricle hypertrophy, abnormal cardiovascular system physiology, abnormal myocardial fiber morphology, cardiac fibrosis, abnormal urine homeostasis, abnormal bradykinin level, abnormal blood homeostasis, decreased creatinine clearance, increased circulating aldosterone level, abnormal urination, decreased urine potassium level, abnormal sympathetic nervous system physiology, abnormal aorta tunica media morphology, increased renin activity, increased angiotensin I-converting enzyme activity, increased mean systemic arterial blood pressure, decreased ventricle muscle contractility, hypertension, increased circulating adrenaline level, abnormal angiogenesis
Affected Gene: Vav3
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI