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Proper Citation: RRID:MGI:3629514
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal joint morphology, increased cell migration, enhanced wound healing, increased circulating tumor necrosis factor level, increased fibroblast cell migration, increased cell proliferation, abnormal aortic valve morphology, thick aortic valve, increased fibroblast proliferation, decreased cardiac output, cardiac fibrosis, aortic valve stenosis, abnormal aortic valve flow, abnormal aorta bulb morphology, abnormal cytotoxic T cell physiology, increased CD8-positive, alpha-beta T cell number, small intestinal inflammation, abnormal response to transplant, increased apoptosis, enlarged spleen, abnormal myelopoiesis, prolonged QT interval, increased tumor necrosis factor secretion, decreased heart rate, decreased ventricle muscle contractility
Affected Gene: Tnf
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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