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Proper Citation: RRID:MGI:3629097
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal lipid homeostasis, abnormal gas homeostasis, cardiac edema, decreased ventricle muscle contractility, increased gonadal fat pad weight, increased inguinal fat pad weight, abnormal white adipose tissue morphology, increased body mass index, increased body weight, increased brown adipose tissue amount, increased circulating leptin level, increased triglyceride level, hepatic steatosis, abnormal myocardium layer morphology, abnormal cardiomyocyte apoptosis, abnormal cardiovascular system physiology, abnormal myocardial fiber morphology, thick interventricular septum, cardiac fibrosis, increased heart weight, premature death, increased interscapular fat pad weight, abnormal brown adipose tissue morphology, decreased circulating glucose level, abnormal respiratory quotient, pulmonary vascular congestion, dilated heart right ventricle, dilated heart left ventricle, decreased circulating triglyceride level, increased insulin sensitivity, improved glucose tolerance, decreased circulating insulin level, abnormal homeostasis, abnormal circulating glucose level, abnormal circulating insulin level, decreased circulating free fatty acid level, decreased circulating VLDL triglyceride level, abnormal glucose tolerance, decreased circulating HDL cholesterol level, impaired adaptive thermogenesis, decreased oxygen consumption, congestive heart failure, impaired lipolysis, abnormal heart morphology, abnormal circulating hormone level
Affected Gene: Pnpla2
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI