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Proper Citation: RRID:MGI:3623773
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: dilated gastric glands, small scala media, abnormal semicircular canal morphology, abnormal mucous neck cell morphology, abnormal gastric parietal cell morphology, abnormal gastric chief cell morphology, stomach mucosa hyperplasia, absent organ of Corti supporting cells, detached otolithic membrane, abnormal inner ear vestibule morphology, cardiovascular system phenotype, circling, collapsed Reissner membrane, enlarged stomach, increased circulating gastrin level, absent cochlear hair cells, circling, head bobbing, hyperactivity, head bobbing, collapsed Reissner membrane, small scala media, abnormal stria vascularis morphology, hyperactivity, increased stomach mucosa thickness, thin stria vascularis, organ of Corti degeneration, stereotypic behavior, organ of Corti degeneration, absent vestibular hair cells, absent vestibular hair cell stereocilia, utricular macular degeneration, abnormal otolith morphology, detached otolithic membrane, spinning, abnormal vestibular labyrinth morphology, increased or absent threshold for auditory brainstem response, absent cochlear hair cells, absent organ of Corti supporting cells, abnormal basilar membrane morphology, cochlear ganglion degeneration, abnormal tectorial membrane morphology, abnormal crista ampullaris morphology, deafness, increased stomach pH, hypochlorhydria
Affected Gene: Kcnq1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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