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Proper Citation: RRID:MGI:3619520
Description: Allele Detail: Spontaneous This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Spontaneous This is a legacy resource.
Phenotype: increased total lung capacity, heart right ventricle hypertrophy, abnormal pulmonary alveolus morphology, skin fibrosis, abnormal skin physiology, abnormal hypodermis morphology, increased mast cell number, abnormal cutaneous microfibril morphology, polyuria, abnormal urinary bladder morphology, abnormal urinary bladder physiology, increased autoantibody level, abnormal aorta tunica adventitia morphology, abnormal pulmonary alveolus morphology, alveolitis, abnormal pulmonary alveolus wall morphology, overexpanded pulmonary alveoli, abnormal alveolar pore morphology, dilated pulmonary alveolar ducts, homeostasis/metabolism phenotype, abnormal lung morphology, alveolitis, overexpanded pulmonary alveoli, dilated pulmonary alveolar ducts, emphysema, abnormal pulmonary alveolus morphology, abnormal heart morphology, abnormal heart morphology, cardiac fibrosis, abnormal skin physiology, overexpanded pulmonary alveoli, skin fibrosis, abnormal cutaneous collagen fibril morphology, thick skin, abnormal uterine NK cell morphology, increased total lung capacity, increased autoantibody level, lung inflammation, increased lung compliance, abnormal bronchiole morphology, emphysema, abnormal alveolar pore morphology, increased lung compliance, alveolitis, abnormal pulmonary alveolus morphology, lung inflammation, abnormal heart right ventricle morphology, emphysema, cardiac fibrosis, thick pulmonary interalveolar septum, emphysema, abnormal pulmonary alveolus morphology, abnormal pulmonary interalveolar septum morphology, abnormal skin morphology, increased susceptibility to type IV hypersensitivity reaction
Affected Gene: Fbn1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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