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Proper Citation: RRID:MGI:3054405
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased insulin secretion, increased systemic arterial blood pressure, decreased pituitary hormone level, increased pancreatic alpha cell proliferation, abnormal pancreatic beta cell differentiation, decreased pancreatic beta cell number, increased pancreatic alpha cell mass, abnormal pancreatic islet morphology, increased pancreatic delta cell number, reduced female fertility, abnormal gland physiology, abnormal pancreatic somatostatin secretion, decreased circulating glucose level, decreased circulating insulin level, decreased glucagon secretion, impaired glucose tolerance
Affected Gene: Pcsk2
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI