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Proper Citation: RRID:MGI:2683655
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal T cell physiology, decreased IgG1 level, decreased interferon-gamma secretion, arrested B cell differentiation, decreased transitional stage T2 B cell number, increased immature B cell number, decreased double-positive T cell number, decreased follicular B cell number, decreased immunoglobulin level, impaired wound healing, decreased marginal zone B cell number, abnormal enterocyte morphology, abnormal B cell physiology, intestinal ulcer, decreased IgM level, decreased IgG3 level, decreased B cell proliferation, decreased IgG2b level, decreased interleukin-2 secretion, decreased T cell proliferation, increased transitional stage T1 B cell number, decreased mature B cell number, decreased T cell number, abnormal humoral immune response, decreased single-positive T cell number, decreased thymocyte number, arrested T cell differentiation
Affected Gene: Vav1, Vav3, Vav2
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No rating or validation information has been found for Vav2tm1Kdf/Vav2tm1Kdf; Vav1tm1Tyb/Vav1tm1Tyb; Vav3tm1Swat/Vav3tm1Swat.
No alerts have been found for Vav2tm1Kdf/Vav2tm1Kdf; Vav1tm1Tyb/Vav1tm1Tyb; Vav3tm1Swat/Vav3tm1Swat.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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