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Proper Citation: RRID:MGI:2670876
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal intestinal goblet cell morphology, decreased small intestinal villus height, abnormal enterocyte proliferation, prolonged QRS complex duration, decreased heart rate, decreased circulating thyroxine level, decreased ventricle muscle contractility, osteosclerosis, delayed endochondral bone ossification, decreased osteoclast cell number, decreased width of hypertrophic chondrocyte zone, abnormal trabecular bone morphology, skeleton phenotype, increased long bone epiphyseal plate size, short tail, short tibia, decreased circulating insulin-like growth factor I level, decreased circulating thyroxine level, increased bone mass, decreased compact bone thickness, postnatal growth retardation, abnormal response/metabolism to endogenous compounds, abnormal osteoclast physiology, abnormal long bone epiphyseal plate morphology, abnormal bone structure, decreased body weight, abnormal chondrocyte physiology, increased trabecular bone thickness, decreased activity of thyroid gland, short limbs, abnormal enterocyte physiology, abnormal enzyme/coenzyme activity, abnormal intestinal mucosa morphology
Affected Gene: Thra
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI