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Proper Citation: RRID:MGI:2660763
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal myelopoiesis, decreased lymphocyte cell number, decreased T cell number, decreased B cell number, abnormal granulocyte differentiation, decreased neutrophil cell number, abnormal vestibular system physiology, deafness, abnormal cochlear outer hair cell morphology, abnormal outer hair cell stereociliary bundle morphology, cochlear outer hair cell degeneration, abnormal cochlear inner hair cell morphology, abnormal inner hair cell stereociliary bundle morphology, short inner hair cell stereocilia, increased interleukin-10 secretion, decreased body weight, abnormal monocyte differentiation, abnormal cytokine secretion, decreased thymocyte number, premature death, abnormal T cell differentiation, decreased granulocyte number, increased susceptibility to endotoxin shock, increased tumor necrosis factor secretion, increased interleukin-1 beta secretion
Affected Gene: Gfi1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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