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Proper Citation: RRID:MGI:2651618
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased circulating interleukin-3 level, increased lymphocyte cell number, increased inflammatory response, abnormal neutrophil morphology, increased neutrophil cell number, increased monocyte cell number, abnormal T cell proliferation, abnormal leukocyte physiology, abnormal immune system cell morphology, abnormal lymph organ size, dermatitis, epidermal hyperplasia, increased IgM level, increased immunoglobulin level, myeloid hyperplasia, enlarged lymph nodes, increased leukocyte cell number, perinatal lethality, incomplete penetrance, alopecia, enlarged spleen, increased circulating interleukin-6 level, abnormal neutrophil physiology, reddish skin, increased susceptibility to bacterial infection, conjunctivitis, increased bone marrow cell number, increased IgG level, increased IgA level
Affected Gene: Itgb2
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI