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Proper Citation: RRID:MGI:2451081
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal choroid plexus morphology, increased circulating LDL cholesterol level, abnormal interscapular fat pad morphology, increased spleen weight, abnormal intestine morphology, abnormal intestinal mucosa morphology, abnormal spleen morphology, abnormal hepatocyte morphology, increased liver triglyceride level, decreased body weight, abnormal liver sinusoid morphology, abnormal adrenal gland morphology, premature death, abnormal spleen morphology, abnormal jejunum morphology, enlarged spleen, abnormal white fat cell size, abnormal small intestinal villus morphology, decreased brown adipose tissue amount, abnormal retroperitoneal fat pad morphology, pale kidney, abnormal inguinal fat pad morphology, increased circulating insulin level, insulin resistance, lung inflammation, abnormal lung morphology, increased type II pneumocyte number, increased food intake, increased liver weight, decreased subcutaneous adipose tissue amount, absent subcutaneous adipose tissue, abnormal alveolar macrophage morphology, decreased epididymal fat pad weight, abnormal hepatocyte morphology, decreased white adipose tissue amount, decreased circulating HDL cholesterol level, increased circulating free fatty acid level, abnormal lipid level, abnormal brown adipose tissue morphology, abnormal small intestine morphology, abnormal duodenum morphology, enlarged mesenteric lymph nodes, increased spleen weight, hepatic steatosis, enlarged liver, increased brown fat cell lipid droplet size, abnormal Kupffer cell morphology, increased liver cholesterol level, abnormal liver morphology, increased liver weight, abnormal pulmonary alveolus morphology, chronic inflammation, abnormal type II pneumocyte morphology, increased Clara cell number, emphysema
Affected Gene: Lipa
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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