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Proper Citation: RRID:MGI:2429787
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: glomerulosclerosis, liver inflammation, abnormal lymph node cell ratio, enlarged spleen, decreased hematocrit, anisocytosis, extramedullary hematopoiesis, abnormal splenic cell ratio, infertility, postnatal lethality, incomplete penetrance, glomerular crescent, spleen hyperplasia, chronic inflammation, decreased mean corpuscular volume, glomerulonephritis, oxidative stress, increased circulating ferritin level, liver fibrosis, enlarged lymph nodes, abnormal leukocyte cell number, lung inflammation, decreased erythrocyte cell number, decreased circulating iron level, abnormal iron homeostasis, microcytic anemia, premature death, decreased body size, cachexia, poor grooming, hypoactivity, small testis, decreased hemoglobin content, renal cast, renal tubular necrosis, kidney failure, increased blood urea nitrogen level, increased renal tubule apoptosis, proximal convoluted tubule brush border loss
Affected Gene: Hmox1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI