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Proper Citation: RRID:MGI:2386103
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased CD8-positive, alpha-beta T cell number, increased CD4-positive, alpha beta T cell number, decreased susceptibility to parasitic infection, abnormal cytokine secretion, increased susceptibility to parasitic infection, decreased IgG1 level, abnormal spleen B cell follicle morphology, absent spleen germinal center, abnormal spleen marginal zone morphology, abnormal spleen periarteriolar lymphoid sheath morphology, abnormal lymph node cell ratio, abnormal immune system organ morphology, increased CD8-positive, alpha-beta T cell number, abnormal CD4-positive, alpha beta T cell morphology, decreased CD4-positive, alpha beta T cell number, abnormal immune system morphology, reduced fertility, postnatal growth retardation, abnormal immune system cell morphology, abnormal B cell physiology, abnormal CD4-positive, alpha-beta T cell physiology, abnormal spleen morphology, abnormal immune system physiology, abnormal T cell physiology, decreased CD4-positive, alpha beta T cell number
Affected Gene: H2-Ab1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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