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URL: https://www.jax.org/strain/006021
Proper Citation: RRID:IMSR_JAX:006021
Description: Mus musculus with name NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ from IMSR.
Species: Mus musculus
Synonyms:
NOD.DQ8/Ab<0>. NOD.Cg-H2-Ab1
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|major histocompatibility complex; class II; DQ beta 1|transgene insertion 1; John F Elliott|major histocompatibility complex; class II; DQ alpha 1|CD4 molecule|CD2 molecule; mutant strain|congenic strain: H2-Ab1|HLA-DQB1|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell|HLA-DQA1|CD4|CD2
Affected Gene: histocompatibility 2; class II antigen A; beta 1|major histocompatibility complex; class II; DQ beta 1|transgene insertion 1; John F Elliott|major histocompatibility complex; class II; DQ alpha 1|CD4 molecule|CD2 molecule
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No rating or validation information has been found for NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.
Source: Integrated Animals
Source Database: JAX Mice and Services
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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