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URL: https://www.infrafrontier.eu/emma/strain-details/?q=9930
Proper Citation: RRID:IMSR_EM:09930
Description: Mus musculus with name B6.Cg-Prnptm1Cwe Tg(Prnp*M128*D177N)FFI-10Rchi/Cnrm from IMSR.
Species: Mus musculus
Synonyms:
Tg(FFI-10<+/+>)/Prnp<0/0>. Tg(FFI-10+/+)/Prnp0/0. B6.Cg-Prnp
Notes: gene symbol note: prion protein|transgene insertion FFI-10; Roberto Chiesa; mutant strain: Prnp|Tg(Prnp*M128*D177N)FFI-10Rchi
Affected Gene: prion protein|transgene insertion FFI-10; Roberto Chiesa
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No rating or validation information has been found for B6.Cg-Prnptm1Cwe Tg(Prnp*M128*D177N)FFI-10Rchi/Cnrm.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Creutzfeldt-Jakob disease.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Gerstmann-Straussler-Scheinker syndrome.
Source: Integrated Animals
Source Database: European Mouse Mutant Archive
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