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URL: http://www.tractor.lncc.br
Proper Citation: Tractor db (RRID:SCR_005610)
Description: Database of computationally predicted Transcription Factors and binding sites in gamma-proteobacterial genomes. The user may browse a map containing all known E. coli transcription factors and regulatory interactions that connect them, and retrieve information on the conservation of each regulatory interaction across the 30 organisms included in the database. Downloading the information is straightforward, and navigation tabs added to dynamic pages ease navigation between the five interfaces of the database. The original prediction approach, based on the representation of binding sites through statistical models was complemented by a new approach that uses known E. coli regulatory sites as the basis for a pattern matching search of regulatory sites. The use of both approaches together resulted in a more intensive exploration of the sequence space of each regulator's binding site. These data should aid researchers in the design of microarray experiments and the interpretation of their results. They should also facilitate studies of Comparative Genomics of the regulatory networks of this group of organisms.
Abbreviations: Tractor db
Synonyms: Tractor_DB
Resource Type: database, data or information resource
Defining Citation: PMID:17088283
Keywords: gamma-proteobacterial genome, transcription factor binding site, transcription factor, regulatory network, microarray, comparative genomicis, genome
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National Laboratory for Scientific Computing; Rio de Janeiro; Brazil |
has parent organization |
National Laboratory for Scientific Computing; Rio de Janeiro; Brazil |
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