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URL: http://www.reatapharma.com/
Proper Citation: Reata Pharmaceuticals (RRID:SCR_004040)
Description: Pharmaceutical company focused on investigating experimental oral antioxidative and anti-inflammatory drugs, which dually activate the antioxidative transcription factor Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) and inhibit the pro-inflammatory transcription factor NF-B (nuclear factor kappa-light-chain-enhancer of activated B cells). The antioxidative and anti-inflammatory compounds bardoxolone methyl and RTA 408 are the lead clinical development compounds in their portfolio.
Abbreviations: Reata
Synonyms: Reata Pharmaceuticals Inc.
Resource Type: commercial organization
Keywords: pharmaceutical, drug, immuno-oncology, ophthalmology, cardiovascular, autoimmune, respiratory, antioxidant inflammation modulator, oxidative stress, medicine, dermatology, skin, eye, clinical trial, nrf2, nf-b, bardoxolone methyl, rta 408, transcription, dna, transcription factor
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