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URL: http://www.ebi.ac.uk/efo/
Proper Citation: Experimental Factor Ontology (RRID:SCR_003574)
Description: An application focused ontology modelling the experimental factors in ArrayExpress and Gene Expression Atlas. It has been developed to increase the richness of the annotations that are currently made in the ArrayExpress repository, to promote consistent annotation, to facilitate automatic annotation and to integrate external data. The ontology describes cross-product classes from reference ontologies in area such as disease, cell line, cell type and anatomy. The methodology employed in the development of EFO involves construction of mappings to multiple existing domain specific ontologies, such as the Disease Ontology and Cell Type Ontology. This is achieved using a combination of automated and manual curation steps and the use of a phonetic matching algorithm. The ontology is evaluated with use cases from the ArrayExpress repository and ArrayExpress Atlas. You may also browse the EFO in the NCBO Bioportal. Term submissions are welcome.
Abbreviations: EFO
Resource Type: ontology, data or information resource, controlled vocabulary
Defining Citation: PMID:20200009
Keywords: gene expression, owl, experimental factor, disease, cell line, cell type, anatomy, gold standard
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