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Resource Name
CAROL
RRID:SCR_001800 RRID Copied      
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CAROL (RRID:SCR_001800)
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Resource Information

URL: http://www.sanger.ac.uk/science/tools/carol

Proper Citation: CAROL (RRID:SCR_001800)

Description: Software application that is a combined functional annotation score of non-synonymous coding variants. A major challenge in interpreting whole-exome data is predicting which of the discovered variants are deleterious or neutral. To address this question in silico, they have developed a score called Combined Annotation scoRing toOL (CAROL), which combines information from two bioinformatics tools: PolyPhen-2 and SIFT, in order to improve the prediction of the effect of non-synonymous coding variants. The combination of annotation tools can help improve automated prediction of whole-genome/exome non-synonymous variant functional consequences. (entry from Genetic Analysis Software) The software should run on any UNIX or GNU/Linux system.

Abbreviations: CAROL

Synonyms: Combined Annotation scoRing toOL

Resource Type: software resource, software application

Defining Citation: PMID:22261837

Keywords: gene, genetic, genomic, r, prediction, non-synonymous coding variant

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