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URL: http://www.addgene.org/22270
Proper Citation: RRID:Addgene_22270
Insert Name: SV40 Large T antigen TK1 mutant (E107K)
Bacterial Resistance: Kanamycin
Vector Backbone Description: Backbone Marker:Invitrogen; Backbone Size:2279; Vector Backbone:pENTR1A; Vector Types:Gateway Cloning; Bacterial Resistance:Kanamycin
Comments: Large T antigen K1 mutant can no longer bind and inactivate the Rb, p130 and p107 proteins (DeCaprio et al. 1988, Stubdal et al. 1997). It also fails to activate Akt (Yu and Alwine 2008).
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Source: Addgene