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URL: http://www.addgene.org/22255
Proper Citation: RRID:Addgene_22255
Insert Name: Genetic suppressor element #22, T329A
Organism: Rattus norvegicus
Bacterial Resistance: Ampicillin
Vector Backbone Description: Backbone Size:8712; Vector Backbone:p156RRL-sinPPT-CMV-GFP-PRE/Nhe I; Vector Types:Mammalian Expression, Lentiviral; Bacterial Resistance:Ampicillin
Comments: Encodes amino acids #312-391 of rat p53 to act as a dominant-negative (Ossovskaya et al. 1996, PNAS 93:10309-10314). T329A mutation does not prevent tetramerization of p53 (Mateu et al. Nat Struct Biol. 1999 Feb;6(2):191-8).
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No rating or validation information has been found for pLenti CMV GSE T329A Hygro (w189-4).
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Source: Addgene
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