The Environmental Determinants of Diabetes in the Young (TEDDY) study is a multicenter prospective cohort study that was established to investigate genetic-environmental interactions and the role of environmental factors- such as infectious agents, dietary factors, and psychosocial factors- on the development of islet autoimmunity and T1D in children at increased genetic risk for the disease. A wide array of clinical data and biospecimens were collected from the 8,676 participants at regular follow-up visits beginning at 3 months until they either reached 15 years of age or their T1D diagnosis endpoint.

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