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dkNET community events and announcements in September, 2017

Dear dkNET Community,

dkNET provides updates on activities of interest to the NIDDK-supported community. You could keep up to date on these activities through our Twitter feed @dkNET_info, through our Community Calendar, or through dkNET e-mail list. If you have an event or funding opportunities you'd like to advertise, please contact us info_at_dknet.org.

dkNET Updates:

  • NIDDK services (centers and core facilities) are added to dkNET 

At dkNET homepage, you can now click NIDDK services (table view) to see a list of NIDDK centers and core facilities. You can also search centers and core facilities at dkNET based on your research of interest. For example, if you are looking for diabetes relevant centers and core facilities, there are two methods: (1) Input keyword diabetes, select NIDDK services, then click search (see results), or (2) Click NIDDK service and select diabetes under Facet "related condition"(see results). All NIDDK centers and core facilities have RRIDs (Research Resource Identifiers) for researchers to cite when they use resources or services from the centers or core facilities.

  • RRID Research Resource Identifier information page

We have added a new RRID information page at dkNET.org this month. RRIDs are persistent and unique identifiers. Adding RRIDs to your research resources such as antibodies, model organisms, and tools to your paper or grant! This helps to authenticate your key biological resources and also makes your paper more reproducible, findable, and widely read! dkNET provides resource tracking and resource authentication services via RRIDs. Open a dkNET account to use these services now!

Events in September, 2017

Sep. 7, 2017

JAX Webinar: Essential Tips for Mouse Researchers 

At times, information that can greatly improve research quality and help locate resources more quickly is not easily found in the literature. We know this can be frustrating, particularly for researchers who are new to working with mice. Join us as we share strategies for navigating available databases and discuss how mouse strain choice impacts research data quality and reproducibility. In this webinar, you will learn about the following topics:(1)Easily finding mouse strains (2)The research value of using proper strain nomenclature in your publications (3)Selecting the right mouse strain background (4)Choosing the best controls (5)Ensuring the genetic integrity of your mouse colony (6)Cautionary tales from the literature.

More information: https://www.jax.org/education-and-learning/education-calendar/webinars/2017/092017/essential-tips-sep-7

Sep. 10 - Sep. 14, 2017

58th International Conference on the Bioscience of Lipids 

The international conference on the bioscience of lipids (ICBL) provides an international forum for the presentation and discussion of fundamental investigations in all aspects of lipid research and related applications. ICBL attracts leading as well as young scientists in the field to the conferences.

Location: Zürich, Switzerland  

More information: http://icbl.info/2017/home/conference/

Sep. 11- Sep. 15, 2017

53rd Annual Meeting of the European Association for the Study of Diabetes 

Location: Lisbon, Protugal

More information: https://www.easd.org/annual-meeting/easd-2017.html

Sep. 11- Sep. 15, 2017

CloudMET 2017: Scientific School on Cloud-based Metabolomics Data Analysis and Collaboration 

Students will have the opportunity to learn about current topics in metabolomics, with a slant on the integration of cloud computing technologies where they are beneficial to the effectiveness and efficiency of research and analysis work. The School is targeted at graduate students and early-stage researchers in metabolomics and bioinformatics. Participants should have some metabolomics experience and an interest in computational data analysis. Some scripting experience will be helpful, but not strictly required.

Location: Pula, Province of Cagliari, Italy

More information: http://cloudmet2017.crs4.it/

Sep. 11 - Sep. 15, 2017

Glucose Clamping the Conscious Mouse: A Laboratory Course 

Location: Nashville, Tennessee 

More information: https://www.mmpc.org/shared/clamping.aspx

Sep. 14, 2017 

JAX Webinar: Generating mouse models using CRISPR/CAS

Do you need to generate new mouse models within 3-4 months instead of 1-1.5 years? Revolutionary CRISPR/Cas technology enables rapid, economical model generation through precise genome editing. During this webinar, we will help you understand the potential of CRISPR/Cas to accelerate your research. Join us as we discuss the following topics:(1) Historical landscape of genetically engineered mouse models (2) How CRISPR/Cas technology is used to generate mouse models (3) Advantages and limitations of CRISPR/Cas technology (4) Selection of founders and follow-up breeding.

More information: https://www.jax.org/education-and-learning/education-calendar/webinars/2017/092017/crispr-sep-14#

Sep. 18-19, 2017

Workshop on Developing Precision Medicine Approaches to the Treatment of Severe Obesity in Adolescents: Research Gaps and Opportunities 

This workshop will bring together scientists with expertise in genetics, pediatric obesity, endocrinology, epidemiology, psychology, behavioral medicine, adolescent medicine, bariatric surgery, and other disciplines to discuss and identify 1) what is known regarding the epidemiology and biopsychosocial determinants of severe obesity in adolescents, 2) what is known regarding effectiveness of treatments for severe obesity in adolescents and predictors of response, and 3) gaps and opportunities for future research to develop more effective and targeted treatments for adolescents with severe obesity. The goal of this trans-NIH workshop is to accelerate research that will identify which treatment approaches will be most beneficial for specific patients based on a better understanding of individual differences in genetic endowment, clinical, metabolic, psychological, and behavioral phenotypes, and response to environmental exposures.

More information: https://www.niddk.nih.gov/news/events-calendar/Pages/workshop-developing-precision-medicine-approaches-treatment-severe-obesity-adolescents.aspx

Sep. 28, 2017

Scholarship deadline: Keystone Meeting - Bioenergetics and Metabolic Disease (J4) 

Obesity and type 2 diabetes are major drivers of chronic disease and premature death. A promising strategy to reduce obesity and improve metabolic health is through promoting energy expenditure via thermogenesis, including obligatory(accompanies all metabolic processes) and facultative (adaptive) mechanisms.Obesity and insulin resistance also lead to profound metabolic changes in various cells/tissues that contribute to tissue dysfunction. This conference brings together basic and clinical researchers from industry and academia focused on the study of cellular and organismal energy metabolism in the context of metabolic disease. A variety of approaches and topics will be featured, including: basic mechanisms of mitochondrial and cellular energetics; the emerging role of brown and beige fat in adaptive thermogenesis; central regulation of energy expenditure; and the effects of exercise on muscle and whole-body metabolism. In addition to the plenary sessions, the meeting will feature workshops on emerging research areas and novel therapeutic opportunities. Overall, the goals of the conference are to: 1) Provide a cutting-edge understanding of the basic mechanisms that control cellular and whole-body energetics; 2) Discuss the physiological role of brown fat and other energy expenditure pathways in humans; 3) Consider novel strategies for increasing energy expenditure and combating metabolic disease; and 4) Engage attendees in critical discussions about important areas for future research.
Location: Keystone, CO

Scholarship Deadline: Keystone Symposium - Organ Crosstalk in Obesity and NAFLD 

Neural and humoral communication among peripheral organs and the brain is critical in coordinating whole body energy homeostasis in health and disease. Nutrient and hormone sensing take place in multiple organs with the central nervous system as a site of integration of these diverse signals, governing this coordination. Within this multi-organ framework, the liver occupies a central role in determining systemic glucose and lipid metabolism in obesity and clinically relevant metabolic pathophysiology, particularly non-alcoholic fatty liver disease (NAFLD) and fibrosis. Identification and characterization of the modes and consequences of organ cross-talk is essential to fill existing gaps in knowledge and to promote the development of therapeutic strategies to treat obesity and metabolic disease. This conference brings together experts in the novel, multidisciplinary evaluation of organ cross-talk, using innovative combinations of molecular, genetic, physiological, pharmacological and systems neuroscience approaches to: 1) Provide a unique and timely perspective, and 2) Inspire interactions directed toward basic, clinical and translational research in integrative metabolism. Finally, the joint staging of this conference in conjunction with the conference on “Bioenergetics and Metabolic Disease” will strategically leverage presentations targeting the biology of metabolism and nutrient availability in obesity with those focused on the biology of energy utilization. Taken together, this novel combination will provide a coherent, powerful and comprehensive understanding of and appreciation for the complex.

Location: Keystone, CO

More information: http://www.keystonesymposia.org/index.cfm?e=web.meeting.summary&meetingid=1565&subtab=summary

Sep. 29, 2017

Workshop Registration Deadline: Enhancing Opportunities in Addressing Obesity and Type 2 Diabetes Disparities 

The focus of this meeting is on socioecological approaches to preventing and treating obesity and type 2 diabetes with a specific focus on opportunities to address how socioecological context influences disease risks, as well as engagement in and response to interventions such as lifestyle changes and self-management. The overall workshop objectives are to: (1)identify aspects of the socioecological and health care delivery contexts that may be targeted to reduce obesity and diabetes disparities (2)assess the implications for interventions to reduce and/or eliminate disparities in obesity and diabetes that affect health disparities populations (3)identify important research opportunities to develop and test approaches to reduce or eliminate obesity and diabetes disparities.

Location: Bethesda, MD

More information: https://www.niddk.nih.gov/news/events-calendar/Pages/enhancing-opportunities-addressing-obesity-type-2-diabetes-disparities.aspx

Funding opportunities information and deadlines in September, 2017

Sep. 1, 2017 

Funding Opportunity Application Due Date: NIH Director's Pioneer Award Program (DP1)

The NIH Director’s Pioneer Award complements NIH's traditional, investigator-initiated grant programs by supporting individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges that have the potential to produce an unusually high impact on enhancing health, lengthening life, and reducing illness and disability. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator’s research program or elsewhere. The NIH Director’s Pioneer Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-005.html

Sep. 1, 2017 

Application Deadline: Stanford University Diabetes Research Center Pilot And Feasibility Program 

The Diabetes Research Center (Stanford DRC) is soliciting new Pilot and Feasibility Projects. The focus of the Stanford DRC Pilot and Feasibility Program is to provide seed funds to help develop new investigators as well as support innovative and/or high-risk proposals from more senior investigators involved in any aspect of diabetes related research, including but not limited to basic sciences, economics, population sciences, translational research and clinical research.

More information:  https://sdrc.stanford.edu/pf-2017-application/

Sep. 1, 2017 

Application deadline: Washington University In St. Louis Center For Diabetes Translation Research Pilot And Feasibility Program 

The purpose of the Pilot and Feasibility Program (PFP) of the CDTR is to foster innovative and transformative research designed to eliminate disparities in diabetes. The PFP focuses on type II translational research in diabetes defined as translating interventions with demonstrated efficacy into real-world healthcare settings, communities, and populations at-risk for health disparities. The PFP provides initial research support over limited time periods to eligible investigators exploring the feasibility of ideas or concepts related to the CDTR mission.

More information: https://cdtr.wustl.edu/pilot-and-feasibility-program/

Sep. 8, 2017 

Funding Opportunities Application Due Date: NIH Director's New Innovator Award Program (DP2) 

The NIH Director’s New Innovator Award (DP2) supports a small number of early stage investigators of exceptional creativity who propose bold and highly innovative new research approaches that have the potential to produce a major impact on broad, important problems in biomedical and behavioral research. The NIH Director's New Innovator Award complements ongoing efforts by NIH and its Institutes and Centers to fund early stage investigators through R01 grants, which continue to be the major sources of NIH support for early stage investigators. The NIH Director’s New Innovator Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-006.html

Sep. 12, 2017 

Letter of Intent Due Date: Compound Identification Development Cores (U2C) 

This Funding Opportunity Announcement (FOA) invites applications to establish Compound Identification Development Cores (CIDC) to develop innovative approaches to enhance compound identification of the most significant, biomedically-relevant unknown metabolites. The ultimate goal of this FOA is to expand the repertoire of biologically relevant compounds that can be quickly and inexpensively identified in high throughput metabolomics experiments. An interdisciplinary approach and partnership among metabolomics experts, biomedical researchers, chemists, and computational experts will be integral to the success of this goal, and advances made through this initiative are expected to be catalytic to the field.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-013.html

Sep. 12, 2017 

Letter of Intent Due Date: Metabolomic Data Analysis and Interpretation Tools (U01) 

The goal of this cooperative agreement Funding Opportunity Announcement (FOA) is to address key challenges in analyzing and interpreting metabolomics data by developing novel tools to facilitate metabolomics data analysis and interpretation. Specifically, successful awardees will develop new or enhanced computational approaches or tools that facilitate metabolomics data analysis, interpretation, and integration. Generalizable, scalable, and portable solutions appropriate for scientists with limited expertise in informatics are particularly encouraged. Projects are not intended to supplement ongoing metabolomics analyses, but to provide tools for broader use by the biomedical research community.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-012.html

Sep. 12, 2017 

Letter of Intent Due Date: National Metabolomics Data Repository (NMDR) (U2C)

This Funding Opportunity Announcement (FOA) addresses the need for a robust National Metabolomics Data Repository to store, and make publicly available, raw and processed metabolomic data generated by large NIH programs, individual research grants, and other biomedical research groups. Data, associated metadata, and the essential tools critical for accessing the key information will be housed in a cloud computing environment accessible for searching and reanalysis by the biomedical research community. The Metabolomics Data Repository and Coordination Center (DRCC), created in Stage I of the Common Fund Metabolomics Program, has begun to address this need. In the transition to a National Metabolomics Data Repository, the successful applicant is expected to continue and enhance the current technical capabilities of the Data Repository and create a governance structure that engages the wider metabolomics community to guide the repository’s efforts toward continual technical improvement and expansion and policy development for data deposition, access, and citation.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-011.html

Sep. 12, 2017 

Letter of Intent Due Date: Stakeholder Engagement and Program Coordination Center (SEPCC) (U2C) 

This Funding Opportunity Announcement (FOA) solicits applications to establish a Stakeholder Engagement and Program Coordination Center (SEPCC) to coordinate the required activities of the Common Fund Metabolomics Program Consortium; to engage the stakeholder community in identifying and developing strategies to address outstanding concerns in the application of metabolomics to biomedical research; and to promote use of Consortium resources by the greater biomedical research community. The Common Fund Metabolomics Program views community engagement and multi-directional communication as essential to overcome challenges in realizing the potential of metabolomics in biomedical research.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-014.html

Sep. 15, 2017 

Letter of intent due date: Joslin Diabetes Center Pilot And Feasibility Studies 

As part of the NIH grant that supports Joslin Diabetes Center’s Diabetes and Research Center (DRC), the Pilot & Feasibility (P&F) Program offers funding each year for two studies in the areas of type 1 diabetes, type 2 diabetes or their complications. The P&F awards may be from basic, translational or clinical perspectives. The goal of the P&F Program is to encourage research on diabetes and its complications by two target groups: young diabetes researchers who recently became independent and have not yet received significant NIH or other funding, and seasoned investigators either entering the diabetes field for the first time or exploring a completely new direction.

More information: https://joslinresearch.org/p-f-studies

Sep. 15, 2017 

Funding Opportunity Application Due Date: NIH Director's Transformative Research Awards (R01) 

The NIH Director's Transformative Research Award complements NIH’s traditional, investigator-initiated grant programs by supporting individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Little or no preliminary data are expected. Projects must clearly demonstrate the potential to produce a major impact in a broad area of biomedical or behavioral research. The NIH Director’s Transformative Research Award is a component of the High-Risk, High-Reward Research program of the NIH Common Fund.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-007.html


Sep. 16, 2017 

Application Due Date: Data Science Rotation for Advancing Discovery Trip (RoAD-Trip) 

The BD2K Training Coordinating Center (TCC) has developed the Data Science Rotations for Advancing Discovery (RoAD-Trip) program to specifically foster new collaborations among junior biomedical researchers and senior-level data scientists to address the challenge of translating complex data into new knowledge. There will be a 2-phase application process. During the first phase, the proposal review team will use research abstracts, reported experience, interests and needed resources, to compile a list of possible compatible junior fellows and senior mentors. Fellows and mentors will be offered the opportunity to “like” each other on the provided list of compatible matches, and the review team will finalize the “matching” process. During the second phase, biomedical scientists and mentors will be asked to jointly submit a Research Plan.

More information: https://bigdatau.ini.usc.edu/roadtrip

Sep. 22, 2017 

Funding Opportunity application deadline: NIH Director's Early Independence Award 

Part of the High-Risk, High-Reward Research program, the award supports outstanding junior scientists with the intellect, scientific creativity, drive, and maturity to flourish independently by bypassing the traditional post-doctoral training period. • Must receive doctoral degree or complete medical residency between June 1, 2016 and September 30, 2018 • Must be in non-independent research position at time of application • Requires significant institutional support • Single PI only • Preliminary data not required • $250,000 direct costs per year for up to 5 years • Minimum of 80% research effort in first 2 years

• 3-5 Letters of Reference required

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-17-008.html https://commonfund.nih.gov/earlyindependence

Sep. 24, 2017 

Funding Opportunity Letter of Intend Due Date: Pragmatic Research in Healthcare Settings to Improve Kidney Disease Prevention and Care (R18) 

The purpose of this Research Demonstration and Dissemination Projects (R18) Funding Opportunity Announcement (FOA) is to encourage research applications to test approaches to improve kidney disease prevention and/or treatment in routine healthcare settings. Research applications should be designed to test practical and potentially sustainable strategies that target the prevention or improved care of kidney disease, or the prevention or delay of the complications of kidney disease. The goal of the research is to obtain results that will improve routine healthcare practice and inform healthcare policy for the prevention or management of these conditions.

More information: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-008.html


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